Hydrogels Scaffolds from Rutgers University

Envisiontec Bioplotter

“3D printing is a method of manufacturing in which materials are deposited onto one another in layers to produce three-dimensional structures. This method allows for the fabrication of complex and interconnected architectures needed to mimic the geometry of the native meniscus. The objective of this study was to develop an acellular, biomechanically functional scaffold for partial meniscus regeneration. The central hypothesis was a collagen-infused 3D-printed polymeric scaffold could be fabricated and implanted to 1) mimic the mechanical properties of the native meniscus, 2) be successfully fixed to the remaining native meniscal rim, 3) increase the contact area and reduce peak stresses relative to partial meniscectomy, 4) encourage cell infiltration, extracellular matrix production, and organized tissue deposition, 5) integrate robustly to the surrounding native meniscal tissue, and 6) protect the articular surfaces to prevent or delay degenerative changes.”-SALIM AMIN GHODBANE in A Collagen-Hyaluronan Infused 3D-Printed Polymeric Scaffold for Partial Meniscus Regeneration